This tutorial will introduce the basic concepts of nanotechnology for biomedical scientists, including the novel physical properties inherent to nanostructured materials and their applications in drug delivery, biosensing, etc.
This tutorial will address the basic characteristics of cancer biology. The natural history of cancer progression at the systemic level in man and the process of carcinogenesis at the cellular level will be covered. Changes in cell function which accompany carcinogenic progression will be discussed in the context of how they relate and contribute to progression at the systemic level. Cancer-associated changes at the molecular level and their role in contributing to the cancer cell phenotype will be outlined. Also, opportunities at the cutting edge of biology and clinical medicine that offer a high potential for interfacing with nanotechnology will be highlighted.
This tutorial will discuss the use of preclinical models, including mouse models, in cancer research to evaluate novel therapies. The tutorial will focus on breast cancer with a special emphasis on recent advances in modeling and imaging metastasis in vivo. The overall objective is to demonstrate the utility of these models in translational cancer research.